Summary
A response with redness, heat, swelling and pain that brings immune cells to damaged tissue.
In depth
Damaged cells and mast cells release histamine and cytokines; vessels dilate (heat, redness) and become leaky (swelling), neutrophils arrive, and pain nerves are stimulated. Chronic inflammation contributes to atherosclerosis, arthritis and cancer.
Cytokines trigger the endothelium to express adhesion molecules so leukocytes can leave blood (diapedesis). Resolution uses pro-resolving mediators.
Key idea: acute inflammation is beneficial; chronic inflammation is harmful.
Frequently asked questions
What is Inflammation?
A response with redness, heat, swelling and pain that brings immune cells to damaged tissue.
Which area of biology covers Inflammation, and how advanced is it?
Inflammation is one of the 52 topics in Immunology & Disease. It is rated Beginner, so it suits learners who are starting out in biology. Related topics in this area include Antigens, Transplant Rejection, Immunosenescence.
Can you give an example of Inflammation?
Aspirin reduces inflammation by inhibiting prostaglandin synthesis.
What should I learn before Inflammation?
Inflammation is a Beginner topic, so no earlier topic is required. Other Beginner topics in Immunology & Disease that pair well with it include Immune System, Viruses, Innate Immunity.
What topics are related to Inflammation?
The closest topics to Inflammation are Antigens, Transplant Rejection, Immunosenescence, White Blood Cells. Comparing them side by side is a good way to see how the ideas connect.
How can I check that I understand Inflammation?
Read the summary and the in-depth section, then use the quick check on the interactive lesson for Inflammation. To practise the whole of Immunology & Disease, use the Immunology & Disease quiz.
How is Inflammation different from Antigens?
Inflammation: A response with redness, heat, swelling and pain that brings immune cells to damaged tissue. Antigens: Molecules, usually on pathogens, that trigger an immune response. Read both side by side and note what each one explains.
How should I study Inflammation step by step?
First, read the summary and write the definition in your own words. Second, read the in-depth section and note any example. Third, compare it with Antigens and explain the difference aloud. Finally, take the Immunology & Disease quiz and come back to this page for any question you miss.