Clock genes align metabolic enzymes and hormones with daily feeding and fasting cycles.
Clock genes in the liver and fat regulate glucose and lipid metabolism. Eating late or shift work disrupts rhythms, increasing diabetes risk. Time-restricted eating is being studied.
Clock genes regulate transcription of metabolic enzymes. Meal timing acts as a clock cue. Disruption raises metabolic risk.
Example: night-shift workers have a higher diabetes risk.
Clock genes align metabolic enzymes and hormones with daily feeding and fasting cycles.
Circadian Metabolism is one of the 53 topics in Metabolism & Bioenergetics. It is rated Advanced, so it suits learners who want specialist depth. Related topics in this area include Hormonal Control of Metabolism, Metabolic Syndrome, Ketone Body Metabolism.
Glucose tolerance is lower in the evening than morning.
Work through the Beginner topics in Metabolism & Bioenergetics first, such as Metabolism, Anabolism and Catabolism, ATP, then return to Circadian Metabolism. Advanced topics assume the Intermediate vocabulary.
The closest topics to Circadian Metabolism are Hormonal Control of Metabolism, Metabolic Syndrome, Ketone Body Metabolism, Cori Cycle. Comparing them side by side is a good way to see how the ideas connect.
Read the summary and the in-depth section, then use the quick check on the interactive lesson for Circadian Metabolism. To practise the whole of Metabolism & Bioenergetics, use the Metabolism & Bioenergetics quiz.
Circadian Metabolism: Clock genes align metabolic enzymes and hormones with daily feeding and fasting cycles. Hormonal Control of Metabolism: Insulin, glucagon, cortisol, adrenaline and thyroid hormone coordinate fuel use across tissues. Read both side by side and note what each one explains.
First, read the summary and write the definition in your own words. Second, read the in-depth section and note any example. Third, compare it with Hormonal Control of Metabolism and explain the difference aloud. Finally, take the Metabolism & Bioenergetics quiz and come back to this page for any question you miss.
Insulin, glucagon, cortisol, adrenaline and thyroid hormone coordinate fuel use across tissues.
⚡ Metabolism & BioenergeticsA cluster of high blood pressure, insulin resistance, obesity and dyslipidaemia raising heart disease risk.
⚡ Metabolism & BioenergeticsDuring fasting the liver makes ketones from fatty acids as alternative fuel for the brain.
⚡ Metabolism & BioenergeticsLactate from muscle is converted to glucose in the liver and returned, costing net ATP.
⚡ Metabolism & Bioenergetics