Summary
Bacteria release and detect signalling molecules to coordinate behaviour as population density rises.
In depth
Cells secrete autoinducers (acyl-homoserine lactones in Gram-negatives, peptides in Gram-positives); when the concentration crosses a threshold, genes switch on. First found in Vibrio fischeri's bioluminescence in squid. It controls virulence and biofilms.
Quorum quenching is an anti-virulence idea.
Quorum sensing allows population-level behaviours such as biofilm formation and virulence factor production. Inhibitors may be used as anti-infective strategies.
Remember: it was found in bioluminescent bacteria.
Frequently asked questions
What is Quorum Sensing?
Bacteria release and detect signalling molecules to coordinate behaviour as population density rises.
Which area of biology covers Quorum Sensing, and how advanced is it?
Quorum Sensing is one of the 54 topics in Microbiology. It is rated Advanced, so it suits learners who want specialist depth. Related topics in this area include Two-Component Systems, Plasmids, Biofilms.
What should I learn before Quorum Sensing?
Work through the Beginner topics in Microbiology first, such as Microorganisms, Bacteria, Archaea, then return to Quorum Sensing. Advanced topics assume the Intermediate vocabulary.
What topics are related to Quorum Sensing?
The closest topics to Quorum Sensing are Two-Component Systems, Plasmids, Biofilms, Bacterial Chemotaxis. Comparing them side by side is a good way to see how the ideas connect.
How can I check that I understand Quorum Sensing?
Read the summary and the in-depth section, then use the quick check on the interactive lesson for Quorum Sensing. To practise the whole of Microbiology, use the Microbiology quiz.
How is Quorum Sensing different from Two-Component Systems?
Quorum Sensing: Bacteria release and detect signalling molecules to coordinate behaviour as population density rises. Two-Component Systems: Sensor kinase and response regulator pairs that let bacteria sense and respond to environmental changes. Read both side by side and note what each one explains.
How should I study Quorum Sensing step by step?
First, read the summary and write the definition in your own words. Second, read the in-depth section and note any example. Third, compare it with Two-Component Systems and explain the difference aloud. Finally, take the Microbiology quiz and come back to this page for any question you miss.